Novel coronavirus pneumonia and diabetes, what is the relationship between?
The novel coronavirus pneumonia may cause diabetes in healthy people and cause serious complications in diabetics, a team from 17 new diabetes experts said recently in a letter published in the new England Journal of medicine.
A novel coronavirus, a 20 diabetes expert in the world, was published by the director of Department of Endocrinology and Professor Ji Linong, director of diabetes center of Peking University. The paper says that novel coronavirus pneumonia is associated with a higher risk of dying from the disease in elderly diabetic patients. At the same time, NCV may actually promote normal people to become new diabetic patients.
These studies not only novel coronavirus pneumonia patients with diabetes warning, but also to ordinary diabetic patients, and even the health of the public has alarmed the alarm.
New coronavirus "favors" diabetic patients
"Experts found that novel coronavirus pneumonia in many countries is a large proportion of people with diabetes mellitus, and those who have new crown pneumonia have high risk of entering the ICU and the risk of death." Ji Linong said in an interview with science and technology daily.
Among novel coronavirus pneumonia patients worldwide, novel coronavirus pneumonia is found in 20% to 50% of patients. It is proved that diabetes is one of the underlying diseases that are closely related to the severity of new crown pneumonia infection. Epidemiological observation of novel coronavirus pneumonia areas and reports from some national health centers and hospitals showed that the risk of death from new crown pneumonia among diabetic patients was more than 50% higher than those of patients without diabetes.
Why are there novel coronavirus pneumonia patients with diabetes? Ji Linong explained that this is because patients with diabetes are in a state of hyperglycemia for a long time, and their body's ability to defend against infection is low, and the risk of infection will increase. Meanwhile, the novel coronavirus pneumonia patients with diabetes are more likely to have higher blood sugar and blood glucose fluctuation. In the elderly, the prevalence of type 2 diabetes is high, and cardiovascular diseases are more common. This is also one of the reasons for the high mortality of elderly diabetic patients infected with the new crown virus.
It may induce new onset diabetes in normal people
"From the current understanding of the new coronavirus, it is not as seasonal as the SARS virus. If we do not strengthen prevention, there may be a risk of re outbreak. Therefore, both diabetic patients and the general population should pay more attention to the prevention of new coronavirus Ji said.
Although it has not been confirmed that new coronavirus can induce diabetes, there is evidence that new coronavirus infection may be a factor in inducing diabetes, according to the recommendations.
Experts said that new coronavirus and ACE2 (angiotensin-converting enzyme 2, which is expressed in airway epithelial cells, intestine and pancreas and other tissues, is initially used as the receptor of new coronavirus invading cells). Because of virus infection, the more active ACE2 receptor can increase blood glucose and metabolic abnormalities in diabetic patients, and the potential pancreatic β - cell damage caused by the virus may lead to New coronavirus infection not only aggravates the condition of diabetic patients, but also induces new onset diabetes in normal people.
Glucocorticoids novel coronavirus pneumonia is used in clinical treatment of some new crown pneumonia patients. Glucocorticoid therapy often causes blood sugar fluctuation. If long-term use of glucocorticoid treatment, its risk of diabetes will increase by 36% - 131%.
Strengthening blood glucose management is the best defense measure
Under the new epidemic situation, the treatment and management of chronic diseases, mainly diabetes mellitus, are challenged. According to statistics, the number of diabetic patients in China has reached 130 million, and there is one diabetic in every 10 people. However, the situation of blood glucose control in diabetic patients is not optimistic, and the rate of reaching the standard of blood glucose is only 15.8%.
For patients with novel coronavirus pneumonia novel coronavirus pneumonia or hyperglycemia, Ji Linong said that controlling hyperglycemia can not only reduce the risk of acute complications of diabetes, but also improve the overall prognosis of new crown pneumonia. "Good glycemic control and management is essential to reduce mortality and infection." He stressed.
"Diabetes patients should strengthen the management of blood glucose and metabolism, which is an important first-class prevention means; at the same time, different patients should carry out individualized target management, lifestyle intervention, blood glucose monitoring and corresponding drug treatment. For patients with novel coronavirus pneumonia and diabetes mellitus, we should strictly control blood sugar and improve the prognosis of patients without increasing the risk of hypoglycemia. Insulin has the advantages of no gastrointestinal side effects, obvious hypoglycemic effect, good for tissue repair, timely adjustment of dosage and no contraindications of liver and kidney functions, so insulin should be the first choice of treatment drugs Ji said.
Experts said that for patients with diabetes, strict control of blood sugar, balanced diet and reasonable work and rest, maintain a happy mood, is the best defense against the new coronavirus; at the same time, in the context of the normalization of epidemic prevention and control, it is necessary to do a good job in the management and prevention and control of diabetes, early diagnosis and treatment, control the occurrence and development speed of diabetes and its complications, and strengthen the prevention and control of diabetes and its complications Diabetes prevention and control mechanism construction.
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